HCSGD entry for DCP2
1. General information
| Official gene symbol | DCP2 |
|---|---|
| Entrez ID | 167227 |
| Gene full name | decapping mRNA 2 |
| Other gene symbols | NUDT20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IMP | biological_process |
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000932 | Cytoplasmic mRNA processing body | IDA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006402 | MRNA catabolic process | IDA IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0016442 | RISC complex | IDA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0016896 | Exoribonuclease activity, producing 5'-phosphomonoesters | TAS | molecular_function |
| GO:0030145 | Manganese ion binding | IEA | molecular_function |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
| GO:0050072 | M7G(5')pppN diphosphatase activity | IDA | molecular_function |
| GO:0071044 | Histone mRNA catabolic process | IMP | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9839144257 | 0.0235580981 | 0.9999902473 | 0.2958362118 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0968172055 |
| GSE13712_SHEAR | Up | 0.0050512305 |
| GSE13712_STATIC | Down | -0.2722890791 |
| GSE19018 | Down | -0.2752955281 |
| GSE19899_A1 | Up | 0.0074811566 |
| GSE19899_A2 | Down | -1.1098931759 |
| PubMed_21979375_A1 | Up | 0.3964975810 |
| PubMed_21979375_A2 | Down | -0.6808665605 |
| GSE35957 | Down | -0.3521659722 |
| GSE36640 | Down | -0.7008087896 |
| GSE54402 | Down | -0.1645739308 |
| GSE9593 | Down | -0.4995417594 |
| GSE43922 | Up | 0.0498387867 |
| GSE24585 | Down | -0.2495357822 |
| GSE37065 | Down | -0.1373231102 |
| GSE28863_A1 | Up | 0.1602666030 |
| GSE28863_A2 | Up | 0.2760174343 |
| GSE28863_A3 | Down | -0.5966451218 |
| GSE28863_A4 | Down | -0.2443293998 |
| GSE48662 | Down | -0.2446410527 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017959 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019392 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021984 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030494 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-320a | MIMAT0000510 | MIRT044464 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048999 | CLASH | Functional MTI (Weak) | 23622248 |
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