HCSGD entry for DCP2


1. General information

Official gene symbolDCP2
Entrez ID167227
Gene full namedecapping mRNA 2
Other gene symbolsNUDT20
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIMPbiological_process
GO:0000288Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTASbiological_process
GO:0000932Cytoplasmic mRNA processing bodyIDAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006402MRNA catabolic processIDA IEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0016442RISC complexIDAcellular_component
GO:0016787Hydrolase activityIEAmolecular_function
GO:0016896Exoribonuclease activity, producing 5'-phosphomonoestersTASmolecular_function
GO:0030145Manganese ion bindingIEAmolecular_function
GO:0043928Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decayTASbiological_process
GO:0050072M7G(5')pppN diphosphatase activityIDAmolecular_function
GO:0071044Histone mRNA catabolic processIMPbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolyticTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98391442570.02355809810.99999024730.2958362118

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0968172055
GSE13712_SHEARUp0.0050512305
GSE13712_STATICDown-0.2722890791
GSE19018Down-0.2752955281
GSE19899_A1Up0.0074811566
GSE19899_A2Down-1.1098931759
PubMed_21979375_A1Up0.3964975810
PubMed_21979375_A2Down-0.6808665605
GSE35957Down-0.3521659722
GSE36640Down-0.7008087896
GSE54402Down-0.1645739308
GSE9593Down-0.4995417594
GSE43922Up0.0498387867
GSE24585Down-0.2495357822
GSE37065Down-0.1373231102
GSE28863_A1Up0.1602666030
GSE28863_A2Up0.2760174343
GSE28863_A3Down-0.5966451218
GSE28863_A4Down-0.2443293998
GSE48662Down-0.2446410527

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017959MicroarrayFunctional MTI (Weak)18185580
hsa-miR-148b-3pMIMAT0000759MIRT019392MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT021984MicroarrayFunctional MTI (Weak)17612493
hsa-miR-24-3pMIMAT0000080MIRT030494MicroarrayFunctional MTI (Weak)19748357
hsa-miR-320aMIMAT0000510MIRT044464CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048999CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.