HCSGD entry for DEFB1
1. General information
| Official gene symbol | DEFB1 |
|---|---|
| Entrez ID | 1672 |
| Gene full name | defensin, beta 1 |
| Other gene symbols | BD1 DEFB-1 DEFB101 HBD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002526 | Acute inflammatory response | IEA | biological_process |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0009617 | Response to bacterium | IDA ISS | biological_process |
| GO:0033574 | Response to testosterone | IEA | biological_process |
| GO:0042742 | Defense response to bacterium | IEA | biological_process |
| GO:0045087 | Innate immune response | ISS NAS TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7763882147 | 0.5897775274 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0822998578 |
| GSE13712_SHEAR | Up | 0.0536114109 |
| GSE13712_STATIC | Down | -0.0977443095 |
| GSE19018 | Up | 0.1056250430 |
| GSE19899_A1 | Down | -0.0568044925 |
| GSE19899_A2 | Up | 0.0836538957 |
| PubMed_21979375_A1 | Down | -0.2735199976 |
| PubMed_21979375_A2 | Down | -0.2557703509 |
| GSE35957 | Down | -0.0674574915 |
| GSE36640 | Down | -0.0434575799 |
| GSE54402 | Down | -0.0122603493 |
| GSE9593 | Up | 0.0229980975 |
| GSE43922 | Up | 0.0499740324 |
| GSE24585 | Down | -0.0154549535 |
| GSE37065 | Up | 0.1664589617 |
| GSE28863_A1 | Up | 0.0575657493 |
| GSE28863_A2 | Down | -0.0923365182 |
| GSE28863_A3 | Up | 0.1597395193 |
| GSE28863_A4 | Down | -0.0456932971 |
| GSE48662 | Up | 0.1223044718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
