HCSGD entry for DEFA5
1. General information
| Official gene symbol | DEFA5 |
|---|---|
| Entrez ID | 1670 |
| Gene full name | defensin, alpha 5, Paneth cell-specific |
| Other gene symbols | DEF5 HD-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0030133 | Transport vesicle | IEA | cellular_component |
| GO:0031640 | Killing of cells of other organism | IEA | biological_process |
| GO:0034774 | Secretory granule lumen | TAS | cellular_component |
| GO:0042742 | Defense response to bacterium | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050832 | Defense response to fungus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9096539911 | 0.6552166863 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0534476069 |
| GSE13712_SHEAR | Down | -0.1596548460 |
| GSE13712_STATIC | Down | -0.0469381278 |
| GSE19018 | Up | 0.1073224196 |
| GSE19899_A1 | Up | 0.1002121916 |
| GSE19899_A2 | Up | 0.0170099638 |
| PubMed_21979375_A1 | Up | 0.0648033746 |
| PubMed_21979375_A2 | Down | -0.0621849495 |
| GSE35957 | Up | 0.2079723574 |
| GSE36640 | Up | 0.0063823587 |
| GSE54402 | Down | -0.1025260842 |
| GSE9593 | Up | 0.0407037723 |
| GSE43922 | Up | 0.0107231043 |
| GSE24585 | Down | -0.3209946318 |
| GSE37065 | Down | -0.0655799886 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0897703663 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025903 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
