HCSGD entry for SGMS2
1. General information
| Official gene symbol | SGMS2 |
|---|---|
| Entrez ID | 166929 |
| Gene full name | sphingomyelin synthase 2 |
| Other gene symbols | SMS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006686 | Sphingomyelin biosynthetic process | IDA | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0030173 | Integral component of Golgi membrane | IDA | cellular_component |
| GO:0033188 | Sphingomyelin synthase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045203 | Integral component of cell outer membrane | IEA | cellular_component |
| GO:0047493 | Ceramide cholinephosphotransferase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0432430075 | 0.3338212758 | 0.4629399349 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1047987396 |
| GSE13712_SHEAR | Up | 0.7744782712 |
| GSE13712_STATIC | Up | 1.3488414869 |
| GSE19018 | Up | 0.1234479160 |
| GSE19899_A1 | Down | -0.3850382934 |
| GSE19899_A2 | Down | -0.1555585975 |
| PubMed_21979375_A1 | Down | -0.1357446584 |
| PubMed_21979375_A2 | Down | -0.2003662225 |
| GSE35957 | Up | 0.5408512167 |
| GSE36640 | Up | 2.3912861347 |
| GSE54402 | Down | -1.5314849652 |
| GSE9593 | Up | 0.4562655810 |
| GSE43922 | Down | -0.2017173782 |
| GSE24585 | Up | 0.0994685932 |
| GSE37065 | Down | -0.2011820195 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4258921018 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019865 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026582 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040261 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
