HCSGD entry for DEFA1
1. General information
| Official gene symbol | DEFA1 |
|---|---|
| Entrez ID | 1667 |
| Gene full name | defensin, alpha 1 |
| Other gene symbols | DEF1 DEFA2 HNP-1 HP-1 HP1 MRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
| GO:0031640 | Killing of cells of other organism | IEA | biological_process |
| GO:0035578 | Azurophil granule lumen | TAS | cellular_component |
| GO:0042742 | Defense response to bacterium | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050832 | Defense response to fungus | IEA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8839604878 | 0.4930441549 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.2756452567 |
| GSE28863_A2 | Down | -0.5480541716 |
| GSE28863_A3 | Up | 0.3683324769 |
| GSE28863_A4 | Up | 0.1484399353 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028873 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
