HCSGD entry for DHX15
1. General information
| Official gene symbol | DHX15 |
|---|---|
| Entrez ID | 1665 |
| Gene full name | DEAH (Asp-Glu-Ala-His) box helicase 15 |
| Other gene symbols | DBP1 DDX15 HRH2 PRP43 PRPF43 PrPp43p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003724 | RNA helicase activity | TAS | molecular_function |
| GO:0003725 | Double-stranded RNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005689 | U12-type spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008380 | RNA splicing | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9752088446 | 0.0246662019 | 0.9999902473 | 0.3028167444 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0855268459 |
| GSE13712_SHEAR | Down | -0.1078251142 |
| GSE13712_STATIC | Down | -0.2247658088 |
| GSE19018 | Down | -0.5737271634 |
| GSE19899_A1 | Down | -0.2227794650 |
| GSE19899_A2 | Down | -0.2716765293 |
| PubMed_21979375_A1 | Up | 0.1578924787 |
| PubMed_21979375_A2 | Down | -0.1509664291 |
| GSE35957 | Down | -0.3196621579 |
| GSE36640 | Down | -0.7934482046 |
| GSE54402 | Up | 0.2279728545 |
| GSE9593 | Down | -0.3419423226 |
| GSE43922 | Down | -0.0264472124 |
| GSE24585 | Down | -0.3517563621 |
| GSE37065 | Up | 0.1434684786 |
| GSE28863_A1 | Up | 0.1801257336 |
| GSE28863_A2 | Up | 0.3584713766 |
| GSE28863_A3 | Down | -0.7385754221 |
| GSE28863_A4 | Down | -0.1658976017 |
| GSE48662 | Down | -0.7744333277 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002740 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002740 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT041781 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043871 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046931 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050083 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051549 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
