HCSGD entry for DHX9
1. General information
| Official gene symbol | DHX9 |
|---|---|
| Entrez ID | 1660 |
| Gene full name | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| Other gene symbols | DDX9 LKP NDH2 NDHII RHA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0001085 | RNA polymerase II transcription factor binding | IPI | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003724 | RNA helicase activity | TAS | molecular_function |
| GO:0004003 | ATP-dependent DNA helicase activity | TAS | molecular_function |
| GO:0004004 | ATP-dependent RNA helicase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0007623 | Circadian rhythm | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030529 | Ribonucleoprotein complex | IDA | cellular_component |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0032508 | DNA duplex unwinding | TAS | biological_process |
| GO:0034605 | Cellular response to heat | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0070934 | CRD-mediated mRNA stabilization | IMP | biological_process |
| GO:0070937 | CRD-mediated mRNA stability complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8232555222 | 0.0343833897 | 0.9999902473 | 0.3506413018 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2644443193 |
| GSE13712_SHEAR | Up | 0.2193984257 |
| GSE13712_STATIC | Down | -0.0611784836 |
| GSE19018 | Down | -0.3032459199 |
| GSE19899_A1 | Down | -0.0821390756 |
| GSE19899_A2 | Down | -0.9350163460 |
| PubMed_21979375_A1 | Down | -0.7317172564 |
| PubMed_21979375_A2 | Down | -0.9863208231 |
| GSE35957 | Up | 0.3077785890 |
| GSE36640 | Down | -0.8667583724 |
| GSE54402 | Up | 0.1109201018 |
| GSE9593 | Up | 0.1382307848 |
| GSE43922 | Down | -0.2209878446 |
| GSE24585 | Down | -0.2263780225 |
| GSE37065 | Down | -0.1534491023 |
| GSE28863_A1 | Up | 0.1047630911 |
| GSE28863_A2 | Up | 0.0593550253 |
| GSE28863_A3 | Down | -0.3031048323 |
| GSE28863_A4 | Down | -0.0222251610 |
| GSE48662 | Down | -0.3484714954 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038769 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041017 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045580 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050296 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052356 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052611 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
