HCSGD entry for TMPRSS6
1. General information
| Official gene symbol | TMPRSS6 |
|---|---|
| Entrez ID | 164656 |
| Gene full name | transmembrane protease, serine 6 |
| Other gene symbols | IRIDA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | NAS | biological_process |
| GO:0004252 | Serine-type endopeptidase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006508 | Proteolysis | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0030198 | Extracellular matrix organization | NAS | biological_process |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0042730 | Fibrinolysis | IDA | biological_process |
| GO:0055072 | Iron ion homeostasis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4689910794 | 0.9522283500 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0958049796 |
| GSE13712_SHEAR | Up | 0.0301386018 |
| GSE13712_STATIC | Down | -0.0340569419 |
| GSE19018 | Up | 0.0161819351 |
| GSE19899_A1 | Up | 0.0217367169 |
| GSE19899_A2 | Up | 0.0985020377 |
| PubMed_21979375_A1 | Down | -0.0161040523 |
| PubMed_21979375_A2 | Up | 0.0198453875 |
| GSE35957 | Up | 0.1499132979 |
| GSE36640 | Up | 0.0531885507 |
| GSE54402 | Up | 0.0330159097 |
| GSE9593 | Up | 0.0805279026 |
| GSE43922 | Up | 0.0671348756 |
| GSE24585 | Up | 0.1246392981 |
| GSE37065 | Down | -0.0287098965 |
| GSE28863_A1 | Down | -0.0399640393 |
| GSE28863_A2 | Down | -0.0292588056 |
| GSE28863_A3 | Up | 0.3214532262 |
| GSE28863_A4 | Up | 0.2176044120 |
| GSE48662 | Up | 0.2894726992 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030016 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
