HCSGD entry for DCTN1


1. General information

Official gene symbolDCTN1
Entrez ID1639
Gene full namedynactin 1
Other gene symbolsDAP-150 DP-150 P135
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000776KinetochoreIDAcellular_component
GO:0000922Spindle poleIDAcellular_component
GO:0003774Motor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005869Dynactin complexIEAcellular_component
GO:0005874MicrotubuleIDAcellular_component
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0007067MitosisNASbiological_process
GO:0007399Nervous system developmentNASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0010970Microtubule-based transportIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030286Dynein complexIEAcellular_component
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0031252Cell leading edgeIEAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045502Dynein bindingIEAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00545295010.99139919460.19421799731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1200124761
GSE13712_SHEARDown-0.6137678982
GSE13712_STATICDown-0.0824421375
GSE19018Up0.3559004315
GSE19899_A1Down-0.0493446494
GSE19899_A2Up0.5818532295
PubMed_21979375_A1Up0.2626441728
PubMed_21979375_A2Up2.0015854792
GSE35957Up0.8704897204
GSE36640Up0.8075873060
GSE54402Up0.2701930028
GSE9593Up0.4473139492
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.3903972007
GSE28863_A2Up0.8359058717
GSE28863_A3Up0.3346072845
GSE28863_A4Down-0.0708822083
GSE48662Up0.3620187156

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1296-5pMIMAT0005794MIRT036100CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044073CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048854CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050276CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.