HCSGD entry for DENND2C
1. General information
| Official gene symbol | DENND2C |
|---|---|
| Entrez ID | 163259 |
| Gene full name | DENN/MADD domain containing 2C |
| Other gene symbols | dJ1156J9.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1173384484 | 0.8271733559 | 0.7023364939 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0003957684 |
| GSE13712_SHEAR | Down | -0.2323650587 |
| GSE13712_STATIC | Up | 0.1071950644 |
| GSE19018 | Down | -0.3894434765 |
| GSE19899_A1 | Up | 0.1113168421 |
| GSE19899_A2 | Up | 0.1875095043 |
| PubMed_21979375_A1 | Up | 1.9116678959 |
| PubMed_21979375_A2 | Up | 0.3480657107 |
| GSE35957 | Up | 0.3849130836 |
| GSE36640 | Up | 0.6175884518 |
| GSE54402 | Up | 0.1329147857 |
| GSE9593 | Up | 0.0883725667 |
| GSE43922 | Up | 0.2200222056 |
| GSE24585 | Up | 0.3105140377 |
| GSE37065 | Down | -0.0273090979 |
| GSE28863_A1 | Down | -0.2732890405 |
| GSE28863_A2 | Up | 0.3209443473 |
| GSE28863_A3 | Down | -0.4250980556 |
| GSE28863_A4 | Down | -0.1392209947 |
| GSE48662 | Up | 0.0726736465 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023271 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
