HCSGD entry for DEDD2

1. General information

Official gene symbolDEDD2
Entrez ID162989
Gene full namedeath effector domain containing 2
Other gene symbolsFLAME-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006396RNA processingNASbiological_process
GO:0008625Extrinsic apoptotic signaling pathway via death domain receptorsIMPbiological_process
GO:0016075RRNA catabolic processNASbiological_process
GO:0019725Cellular homeostasisNASbiological_process
GO:0030159Receptor signaling complex scaffold activityNASmolecular_function
GO:0030262Apoptotic nuclear changesIDAbiological_process
GO:0035556Intracellular signal transductionNASbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedNASbiological_process
GO:2001238Positive regulation of extrinsic apoptotic signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00037805170.98702940620.05182613071.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.6566962740
GSE13712_SHEARUp0.4685543356
GSE13712_STATICUp0.2695924764
GSE19018Up0.4657460430
GSE19899_A1Up2.1027109333
GSE19899_A2Up1.9659123939
PubMed_21979375_A1Up2.6797000516
PubMed_21979375_A2Up1.6711044491
GSE35957Up0.0705296413
GSE36640Up0.9564257333
GSE54402Up1.2900019207
GSE9593Up0.5715257265
GSE43922Up0.7932408349
GSE24585Up0.0057104492
GSE37065Up0.2033876232
GSE28863_A1Down-0.5402794573
GSE28863_A2Up0.0063898132
GSE28863_A3Down-0.2210044251
GSE28863_A4Up0.0285287188
GSE48662Up0.2060273796

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-92a-3pMIMAT0000092MIRT049538CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.