HCSGD entry for ZNF497

1. General information

Official gene symbol	ZNF497
Entrez ID	162968
Gene full name	zinc finger protein 497
Other gene symbols
Links to Entrez Gene	Links to Entrez Gene

2. Neighbors in the network

This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID	GO term	Evidence	Category
GO:0003677	DNA binding	IEA	molecular_function
GO:0005634	Nucleus	IEA	cellular_component
GO:0006351	Transcription, DNA-templated	IEA	biological_process
GO:0006355	Regulation of transcription, DNA-templated	IEA	biological_process
GO:0046872	Metal ion binding	IEA	molecular_function

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4. Expression levels in datasets

Meta-analysis result

p-value up	p-value down	FDR up	FDR down
0.1735133316	0.9599651837	0.8178804441	1.0000000000

Individual experiment result
( "-" represent NA in the specific microarray platform )

Data source	Up or down	Log fold change
GSE11954	Up	0.0180285710
GSE13712_SHEAR	Down	-0.0196426415
GSE13712_STATIC	Up	0.0720167479
GSE19018	Up	0.1256274462
GSE19899_A1	Up	0.0024132961
GSE19899_A2	Up	0.0236032587
PubMed_21979375_A1	Up	0.5299910305
PubMed_21979375_A2	Down	-0.0578065710
GSE35957	Down	-0.0028917380
GSE36640	Up	0.7977118334
GSE54402	Up	0.1203042245
GSE9593	Down	-0.0396628381
GSE43922	-	-
GSE24585	-	-
GSE37065	-	-
GSE28863_A1	Down	-0.0216060721
GSE28863_A2	Down	-0.1714492159
GSE28863_A3	Up	0.2328746458
GSE28863_A4	Up	0.0349696570
GSE48662	Up	1.1040164912

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Not regulated by compounds

Drugs

Not regulated by drugs

MicroRNAs

mirTarBase

No target information from mirTarBase

mirRecord

No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.

PubMed ID of the article	Sentenece the gene occurs
21212468	Zfra (zinc finger-like protein that regulates apoptosis) is a naturally occurring short peptide consisting of 31 amino acids, which regulates tumor necrosis factor (TNF)-mediated cell death by interacting with receptor adaptor protein TRADD (TNF receptorassociated death domain protein) and downstream JNK (c-Jun N-terminal kinase), NF-kappaB (Nuclear factor kappa B) and WWOX/WOX1 (WW domain-containing oxidoreductase)

PubMed ID of the article

Sentenece the gene occurs

21212468

Zfra (zinc finger-like protein that regulates apoptosis) is a naturally occurring short peptide consisting of 31 amino acids, which regulates tumor necrosis factor (TNF)-mediated cell death by interacting with receptor adaptor protein TRADD (TNF receptorassociated death domain protein) and downstream JNK (c-Jun N-terminal kinase), NF-kappaB (Nuclear factor kappa B) and WWOX/WOX1 (WW domain-containing oxidoreductase)