HCSGD entry for DBT
1. General information
| Official gene symbol | DBT |
|---|---|
| Entrez ID | 1629 |
| Gene full name | dihydrolipoamide branched chain transacylase E2 |
| Other gene symbols | BCATE2 BCKAD-E2 BCKADE2 E2 E2B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005947 | Mitochondrial alpha-ketoglutarate dehydrogenase complex | TAS | cellular_component |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0043754 | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046949 | Fatty-acyl-CoA biosynthetic process | IEA | biological_process |
| GO:0048037 | Cofactor binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1717282170 | 0.7875248509 | 0.8141753013 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0303088436 |
| GSE13712_SHEAR | Up | 0.4398483851 |
| GSE13712_STATIC | Up | 0.2527681008 |
| GSE19018 | Up | 0.0337766504 |
| GSE19899_A1 | Up | 0.0237349219 |
| GSE19899_A2 | Down | -0.2176753468 |
| PubMed_21979375_A1 | Down | -0.3081518432 |
| PubMed_21979375_A2 | Down | -0.0107599569 |
| GSE35957 | Up | 0.1066292271 |
| GSE36640 | Up | 0.0383432024 |
| GSE54402 | Down | -0.2907110388 |
| GSE9593 | Down | -0.0157481451 |
| GSE43922 | Down | -0.1341907554 |
| GSE24585 | Up | 0.3275630929 |
| GSE37065 | Up | 0.0930491068 |
| GSE28863_A1 | Up | 0.5106698917 |
| GSE28863_A2 | Up | 0.5213309320 |
| GSE28863_A3 | Down | -0.3840884377 |
| GSE28863_A4 | Down | -0.0173036428 |
| GSE48662 | Up | 0.6478227125 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023019 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024650 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026763 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043092 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
