HCSGD entry for NAGS
1. General information
| Official gene symbol | NAGS |
|---|---|
| Entrez ID | 162417 |
| Gene full name | N-acetylglutamate synthase |
| Other gene symbols | AGAS ARGA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000050 | Urea cycle | TAS | biological_process |
| GO:0004042 | Acetyl-CoA:L-glutamate N-acetyltransferase activity | TAS | molecular_function |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006526 | Arginine biosynthetic process | IEA | biological_process |
| GO:0006536 | Glutamate metabolic process | TAS | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5049427187 | 0.1517895179 | 0.9999902473 | 0.7522598192 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0393869988 |
| GSE13712_SHEAR | Up | 0.4784386679 |
| GSE13712_STATIC | Down | -0.1786724348 |
| GSE19018 | Up | 0.0059919815 |
| GSE19899_A1 | Down | -0.0396198346 |
| GSE19899_A2 | Down | -0.6585577532 |
| PubMed_21979375_A1 | Down | -0.9220775201 |
| PubMed_21979375_A2 | Down | -0.3542180144 |
| GSE35957 | Down | -0.3169476631 |
| GSE36640 | Down | -0.4669602415 |
| GSE54402 | Up | 0.8676808554 |
| GSE9593 | Down | -0.3067849641 |
| GSE43922 | Up | 0.0969123644 |
| GSE24585 | Up | 0.2024853106 |
| GSE37065 | Down | -0.0271578867 |
| GSE28863_A1 | Down | -0.1946596737 |
| GSE28863_A2 | Down | -0.1144665127 |
| GSE28863_A3 | Up | 0.3612198744 |
| GSE28863_A4 | Up | 0.0819307226 |
| GSE48662 | Down | -0.0441562780 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
