HCSGD entry for DBH

1. General information

Official gene symbolDBH
Entrez ID1621
Gene full namedopamine beta-hydroxylase (dopamine beta-monooxygenase)
Other gene symbolsDBM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001816Cytokine productionIEAbiological_process
GO:0001974Blood vessel remodelingIEAbiological_process
GO:0001975Response to amphetamineIEAbiological_process
GO:0002443Leukocyte mediated immunityIEAbiological_process
GO:0003824Catalytic activityTASmolecular_function
GO:0004500Dopamine beta-monooxygenase activityIEA TASmolecular_function
GO:0005507Copper ion bindingIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005737CytoplasmTAScellular_component
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007613MemoryIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008542Visual learningIEAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030658Transport vesicle membraneIEAcellular_component
GO:0031418L-ascorbic acid bindingIEAmolecular_function
GO:0034466Chromaffin granule lumenIEAcellular_component
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0034774Secretory granule lumenTAScellular_component
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0042309HomoiothermyIEAbiological_process
GO:0042420Dopamine catabolic processIEAbiological_process
GO:0042421Norepinephrine biosynthetic processIEAbiological_process
GO:0042423Catecholamine biosynthetic processTASbiological_process
GO:0042584Chromaffin granule membraneIEAcellular_component
GO:0042593Glucose homeostasisIEAbiological_process
GO:0042596Fear responseIEAbiological_process
GO:0042711Maternal behaviorIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045907Positive regulation of vasoconstrictionIEAbiological_process
GO:0048149Behavioral response to ethanolIEAbiological_process
GO:0048265Response to painIEAbiological_process
GO:0050900Leukocyte migrationIEAbiological_process
GO:2001236Regulation of extrinsic apoptotic signaling pathwayIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33539349950.92307530490.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1565947323
GSE13712_SHEARUp0.1569056115
GSE13712_STATICUp0.0616839501
GSE19018Up0.1983359811
GSE19899_A1Up0.1783631189
GSE19899_A2Up0.1066619093
PubMed_21979375_A1Down-0.3288827338
PubMed_21979375_A2Down-0.1057330857
GSE35957Up0.3287539360
GSE36640Down-0.1371600801
GSE54402Up0.0098231568
GSE9593Up0.2189005898
GSE43922Up0.0820599119
GSE24585Up0.0265748645
GSE37065Up0.0161770976
GSE28863_A1Up0.0990403793
GSE28863_A2Up0.1995391339
GSE28863_A3Up0.2573287775
GSE28863_A4Up0.0486869562
GSE48662Up0.0012534849

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541
DisulfiramDB00822 APRD00767

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017290MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.