HCSGD entry for SYNE3
1. General information
| Official gene symbol | SYNE3 |
|---|---|
| Entrez ID | 161176 |
| Gene full name | spectrin repeat containing, nuclear envelope family member 3 |
| Other gene symbols | C14orf49 NET53 Nesp3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005635 | Nuclear envelope | IDA | cellular_component |
| GO:0005640 | Nuclear outer membrane | IEA | cellular_component |
| GO:0007010 | Cytoskeleton organization | IMP | biological_process |
| GO:0008360 | Regulation of cell shape | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034993 | SUN-KASH complex | IDA | cellular_component |
| GO:0051015 | Actin filament binding | IMP | molecular_function |
| GO:0090150 | Establishment of protein localization to membrane | IDA | biological_process |
| GO:0090286 | Cytoskeletal anchoring at nuclear membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2276894647 | 0.4837943581 | 0.9096428008 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1729709958 |
| GSE13712_SHEAR | Down | -0.1191504944 |
| GSE13712_STATIC | Down | -0.1175994121 |
| GSE19018 | Up | 0.1718262252 |
| GSE19899_A1 | Up | 0.1177504264 |
| GSE19899_A2 | Up | 0.0002105023 |
| PubMed_21979375_A1 | Down | -0.5548782886 |
| PubMed_21979375_A2 | Up | 0.0927078528 |
| GSE35957 | Down | -0.2692937001 |
| GSE36640 | Up | 0.1176096619 |
| GSE54402 | Down | -0.1046684015 |
| GSE9593 | Up | 0.1512200115 |
| GSE43922 | Down | -0.7355728069 |
| GSE24585 | Down | -0.0653575389 |
| GSE37065 | Down | -0.3285168092 |
| GSE28863_A1 | Up | 0.8312046616 |
| GSE28863_A2 | Up | 0.6670228759 |
| GSE28863_A3 | Down | -0.0879213344 |
| GSE28863_A4 | Up | 0.1717353776 |
| GSE48662 | Up | 0.2431620776 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018850 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021781 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043818 | CLASH | Functional MTI (Weak) | 23622248 |
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