HCSGD entry for DAO
1. General information
| Official gene symbol | DAO |
|---|---|
| Entrez ID | 1610 |
| Gene full name | D-amino-acid oxidase |
| Other gene symbols | DAAO DAMOX OXDA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003884 | D-amino-acid oxidase activity | IDA IEA TAS | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | IDA | cellular_component |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA | cellular_component |
| GO:0005782 | Peroxisomal matrix | TAS | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006551 | Leucine metabolic process | IEA | biological_process |
| GO:0006562 | Proline catabolic process | IDA | biological_process |
| GO:0016641 | Oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0036088 | D-serine catabolic process | IDA | biological_process |
| GO:0042416 | Dopamine biosynthetic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046487 | Glyoxylate metabolic process | TAS | biological_process |
| GO:0046983 | Protein dimerization activity | IDA | molecular_function |
| GO:0048037 | Cofactor binding | IDA IEA | molecular_function |
| GO:0055130 | D-alanine catabolic process | IDA IEA | biological_process |
| GO:0070178 | D-serine metabolic process | IDA | biological_process |
| GO:0071949 | FAD binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6481265757 | 0.6232204058 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0283324959 |
| GSE13712_SHEAR | Down | -0.1349447870 |
| GSE13712_STATIC | Up | 0.3250519067 |
| GSE19018 | Up | 0.0902806670 |
| GSE19899_A1 | Up | 0.0707121675 |
| GSE19899_A2 | Up | 0.1675298663 |
| PubMed_21979375_A1 | Down | -0.1378266465 |
| PubMed_21979375_A2 | Down | -0.2177768332 |
| GSE35957 | Up | 0.0041358628 |
| GSE36640 | Up | 0.0007105946 |
| GSE54402 | Down | -0.0624706647 |
| GSE9593 | Up | 0.0040853502 |
| GSE43922 | Up | 0.1411756012 |
| GSE24585 | Down | -0.1311852864 |
| GSE37065 | Down | -0.0075256887 |
| GSE28863_A1 | Down | -0.1277388260 |
| GSE28863_A2 | Down | -0.0426965297 |
| GSE28863_A3 | Up | 0.4652520209 |
| GSE28863_A4 | Down | -0.0229521824 |
| GSE48662 | Up | 0.0322597195 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 3,4-Dihydro-2h-Pyrrolium-5-Carboxylate | DB02838 | EXPT00141 |
| Imino-Tryptophan | DB02988 | EXPT01942 |
| D-Tryptophan | DB03225 | EXPT01290 |
| Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone | DB03531 | EXPT01389 |
| Benzoic Acid | DB03793 | EXPT00675 |
| 2-Aminobenzoic Acid | DB04166 | EXPT00656 |
| (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID | DB07979 | - |

