HCSGD entry for AP2A2
1. General information
| Official gene symbol | AP2A2 |
|---|---|
| Entrez ID | 161 |
| Gene full name | adaptor-related protein complex 2, alpha 2 subunit |
| Other gene symbols | ADTAB CLAPA2 HIP-9 HIP9 HYPJ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030131 | Clathrin adaptor complex | IEA | cellular_component |
| GO:0030666 | Endocytic vesicle membrane | TAS | cellular_component |
| GO:0042059 | Negative regulation of epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0050690 | Regulation of defense response to virus by virus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0993491699 | 0.8967145321 | 0.6579522516 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0717488555 |
| GSE13712_SHEAR | Down | -0.3344720090 |
| GSE13712_STATIC | Down | -0.1777499566 |
| GSE19018 | Up | 0.2294047495 |
| GSE19899_A1 | Down | -0.0334001676 |
| GSE19899_A2 | Up | 0.3972435589 |
| PubMed_21979375_A1 | Up | 0.8584800825 |
| PubMed_21979375_A2 | Up | 0.9028557002 |
| GSE35957 | Down | -0.0576585236 |
| GSE36640 | Up | 0.1017158956 |
| GSE54402 | Up | 0.1942853911 |
| GSE9593 | Down | -0.0073111339 |
| GSE43922 | Up | 0.0791723432 |
| GSE24585 | Down | -0.1674964766 |
| GSE37065 | Down | -0.4032666715 |
| GSE28863_A1 | Up | 0.4750140805 |
| GSE28863_A2 | Up | 0.2539285175 |
| GSE28863_A3 | Up | 0.1954151627 |
| GSE28863_A4 | Up | 0.0781823901 |
| GSE48662 | Up | 0.4034614390 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025343 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037420 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040723 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043335 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048756 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
