HCSGD entry for DENND5B


1. General information

Official gene symbolDENND5B
Entrez ID160518
Gene full nameDENN/MADD domain containing 5B
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005262Calcium channel activityIBAmolecular_function
GO:0016020MembraneIBAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017112Rab guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0032313Regulation of Rab GTPase activityIDAbiological_process
GO:0032318Regulation of Ras GTPase activityIDAbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
GO:0050982Detection of mechanical stimulusIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46682247630.15174361540.99999024730.7522598192

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2654365278
GSE13712_SHEARUp0.3004653548
GSE13712_STATICUp0.4721860985
GSE19018Up0.3571503650
GSE19899_A1Down-0.1413667668
GSE19899_A2Down-0.4861544215
PubMed_21979375_A1Down-0.9390232346
PubMed_21979375_A2Down-0.0589035759
GSE35957Down-0.1445801125
GSE36640Down-0.0208275612
GSE54402Down-0.5346507554
GSE9593Down-0.0918097799
GSE43922Down-0.3485276919
GSE24585Up0.3470217928
GSE37065Up0.0371008988
GSE28863_A1Up0.6071787103
GSE28863_A2Up0.2588067411
GSE28863_A3Down-0.4763819654
GSE28863_A4Up0.0270241880
GSE48662Up0.0375158039

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.