HCSGD entry for DAD1
1. General information
| Official gene symbol | DAD1 |
|---|---|
| Entrez ID | 1603 |
| Gene full name | defender against cell death 1 |
| Other gene symbols | OST2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001824 | Blastocyst development | IEA | biological_process |
| GO:0004576 | Oligosaccharyl transferase activity | ISS | molecular_function |
| GO:0004579 | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | IC IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006486 | Protein glycosylation | ISS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0008250 | Oligosaccharyltransferase complex | IEA ISS TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | IC TAS | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0361017097 | 0.9781893659 | 0.4316536331 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3040869666 |
| GSE13712_SHEAR | Up | 0.0049319124 |
| GSE13712_STATIC | Down | -0.0306182868 |
| GSE19018 | Up | 0.4859060339 |
| GSE19899_A1 | Up | 0.4639839424 |
| GSE19899_A2 | Up | 0.4261094500 |
| PubMed_21979375_A1 | Up | 0.5100553053 |
| PubMed_21979375_A2 | Up | 0.1489940471 |
| GSE35957 | Up | 0.0758285393 |
| GSE36640 | Up | 0.4304720877 |
| GSE54402 | Up | 0.4069665341 |
| GSE9593 | Up | 0.2459832009 |
| GSE43922 | Up | 0.3996911566 |
| GSE24585 | Up | 0.1121105042 |
| GSE37065 | Down | -0.1588327721 |
| GSE28863_A1 | Down | -0.1610101008 |
| GSE28863_A2 | Down | -0.1135424328 |
| GSE28863_A3 | Up | 0.1800365585 |
| GSE28863_A4 | Up | 0.1268012795 |
| GSE48662 | Down | -0.1388715369 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | NA | hsa-let-7a | 19939273 | |||
| hsa-let-7d-5p | MIMAT0000065 | NA | hsa-let-7d | 19939273 | |||
| hsa-let-7e-5p | MIMAT0000066 | NA | hsa-let-7e | 19939273 | |||
| hsa-let-7g-5p | MIMAT0000414 | NA | hsa-let-7g | 19939273 | |||
| hsa-let-7i-5p | MIMAT0000415 | NA | hsa-let-7i | 19939273 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
