HCSGD entry for NKX2-3

1. General information

Official gene symbolNKX2-3
Entrez ID159296
Gene full nameNK2 homeobox 3
Other gene symbolsCSX3 NK2.3 NKX2.3 NKX2C NKX4-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001776Leukocyte homeostasisIEAbiological_process
GO:0002317Plasma cell differentiationIEAbiological_process
GO:0003674Molecular_functionNDmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006641Triglyceride metabolic processIEAbiological_process
GO:0008150Biological_processNDbiological_process
GO:0022612Gland morphogenesisIEAbiological_process
GO:0030225Macrophage differentiationIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0043367CD4-positive, alpha-beta T cell differentiationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048535Lymph node developmentIEAbiological_process
GO:0048536Spleen developmentIEAbiological_process
GO:0048541Peyer's patch developmentIEAbiological_process
GO:0048621Post-embryonic digestive tract morphogenesisIEAbiological_process
GO:0050900Leukocyte migrationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44048347710.89409559670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0704004607
GSE13712_SHEARDown-0.0833331800
GSE13712_STATICUp0.2929462600
GSE19018Up0.0523956097
GSE19899_A1Up0.1443716769
GSE19899_A2Down-0.0922510881
PubMed_21979375_A1Down-0.0970783698
PubMed_21979375_A2Up0.0158726067
GSE35957Down-0.0729788855
GSE36640Up0.0720784349
GSE54402Down-0.0738918314
GSE9593Up0.0311879452
GSE43922Up0.0123335206
GSE24585Up0.1428239267
GSE37065Down-0.0138149985
GSE28863_A1Up0.1117980918
GSE28863_A2Up0.0018574149
GSE28863_A3Up0.2465545111
GSE28863_A4Up0.1391571596
GSE48662Up0.0339985766

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.