HCSGD entry for CYP4A11

1. General information

Official gene symbolCYP4A11
Entrez ID1579
Gene full namecytochrome P450, family 4, subfamily A, polypeptide 11
Other gene symbolsCP4Y CYP4A2 CYP4AII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001676Long-chain fatty acid metabolic processIDAbiological_process
GO:0003091Renal water homeostasisIEPbiological_process
GO:0003095Pressure natriuresisIEPbiological_process
GO:0004497Monooxygenase activityIEAmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006631Fatty acid metabolic processTASbiological_process
GO:0006691Leukotriene metabolic processIDAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0008392Arachidonic acid epoxygenase activityIDAmolecular_function
GO:0016324Apical plasma membraneIDAcellular_component
GO:0016705Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEAmolecular_function
GO:0018685Alkane 1-monooxygenase activityIDAmolecular_function
GO:0019369Arachidonic acid metabolic processIDA TASbiological_process
GO:0019373Epoxygenase P450 pathwayIDAbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0032305Positive regulation of icosanoid secretionIMPbiological_process
GO:0036101Leukotriene B4 catabolic processIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050051Leukotriene-B4 20-monooxygenase activityIDAmolecular_function
GO:0052869Arachidonic acid omega-hydroxylase activityIEAmolecular_function
GO:0055078Sodium ion homeostasisIEPbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0097267Omega-hydroxylase P450 pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84716224310.82429479880.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0075037048
GSE13712_SHEARDown-0.0302249500
GSE13712_STATICUp0.2047638549
GSE19018Up0.1433658184
GSE19899_A1Up0.1309372745
GSE19899_A2Up0.0795462511
PubMed_21979375_A1Down-0.2968508762
PubMed_21979375_A2Down-0.0142669374
GSE35957Up0.1363871407
GSE36640Down-0.1923687757
GSE54402Down-0.1299488726
GSE9593Up0.0393907140
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0452603210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028966MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.