HCSGD entry for NKX6-3


1. General information

Official gene symbolNKX6-3
Entrez ID157848
Gene full nameNK6 homeobox 3
Other gene symbolsNKX6.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0001709Cell fate determinationIEAbiological_process
GO:0002067Glandular epithelial cell differentiationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0030857Negative regulation of epithelial cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48144613430.74949441510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1918246566
GSE13712_SHEARUp0.1266868789
GSE13712_STATICDown-0.1773508668
GSE19018Up0.2388990287
GSE19899_A1Down-0.0547863135
GSE19899_A2Up0.1159297812
PubMed_21979375_A1Down-0.0733808370
PubMed_21979375_A2Up0.0718566782
GSE35957Up0.1008088912
GSE36640Up0.0515657376
GSE54402Down-0.0413635226
GSE9593Up0.0594634502
GSE43922Up0.4058296977
GSE24585Up0.1060022006
GSE37065Down-0.0002310317
GSE28863_A1Down-0.2516911582
GSE28863_A2Down-0.1682686483
GSE28863_A3Up0.4110954105
GSE28863_A4Down-0.0408177340
GSE48662Up0.0671692899

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.