HCSGD entry for RDH10
1. General information
| Official gene symbol | RDH10 |
|---|---|
| Entrez ID | 157506 |
| Gene full name | retinol dehydrogenase 10 (all-trans) |
| Other gene symbols | SDR16C4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0001656 | Metanephros development | IEA | biological_process |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0002138 | Retinoic acid biosynthetic process | IEA | biological_process |
| GO:0004745 | Retinol dehydrogenase activity | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0007601 | Visual perception | IDA | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0008406 | Gonad development | IEA | biological_process |
| GO:0014032 | Neural crest cell development | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0031076 | Embryonic camera-type eye development | IEA | biological_process |
| GO:0035115 | Embryonic forelimb morphogenesis | IEA | biological_process |
| GO:0042572 | Retinol metabolic process | IDA | biological_process |
| GO:0042574 | Retinal metabolic process | IDA IEA | biological_process |
| GO:0043583 | Ear development | IEA | biological_process |
| GO:0043584 | Nose development | IEA | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0048703 | Embryonic viscerocranium morphogenesis | IEA | biological_process |
| GO:0052650 | NADP-retinol dehydrogenase activity | IEA | molecular_function |
| GO:0060431 | Primary lung bud formation | IEA | biological_process |
| GO:0060449 | Bud elongation involved in lung branching | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0343921887 | 0.1373924167 | 0.4258649741 | 0.7143347938 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1327270151 |
| GSE13712_SHEAR | Up | 0.8840346271 |
| GSE13712_STATIC | Up | 0.8478470672 |
| GSE19018 | Down | -0.4087395746 |
| GSE19899_A1 | Down | -0.9486493627 |
| GSE19899_A2 | Down | -0.4378530529 |
| PubMed_21979375_A1 | Up | 0.7617985784 |
| PubMed_21979375_A2 | Up | 0.8830471342 |
| GSE35957 | Up | 1.0772274577 |
| GSE36640 | Up | 0.3504861888 |
| GSE54402 | Down | -0.8261484876 |
| GSE9593 | Down | -0.1099712726 |
| GSE43922 | Down | -0.1116888119 |
| GSE24585 | Down | -0.4242041551 |
| GSE37065 | Up | 0.2373996383 |
| GSE28863_A1 | Up | 0.0797452569 |
| GSE28863_A2 | Up | 0.9540906659 |
| GSE28863_A3 | Down | -0.5615591117 |
| GSE28863_A4 | Down | -0.1980427406 |
| GSE48662 | Up | 0.9459752383 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001600 | pSILAC//Luciferase reporter assay//Proteomics;Other | Functional MTI | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT003051 | Luciferase reporter assay//Reporter assay | Functional MTI | 17724173 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT003051 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026079 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
