HCSGD entry for ZNF746
1. General information
| Official gene symbol | ZNF746 |
|---|---|
| Entrez ID | 155061 |
| Gene full name | zinc finger protein 746 |
| Other gene symbols | PARIS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0010941 | Regulation of cell death | IDA | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0070997 | Neuron death | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3572433722 | 0.8531143726 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4665693915 |
| GSE13712_SHEAR | Down | -0.1679391727 |
| GSE13712_STATIC | Down | -0.0678952550 |
| GSE19018 | Down | -0.3447889467 |
| GSE19899_A1 | Down | -0.1026562763 |
| GSE19899_A2 | Up | 0.2584706182 |
| PubMed_21979375_A1 | Up | 0.2605264493 |
| PubMed_21979375_A2 | Up | 0.3838626520 |
| GSE35957 | Down | -0.1451084107 |
| GSE36640 | Up | 0.0730007544 |
| GSE54402 | Up | 0.1647618761 |
| GSE9593 | Up | 0.1635481332 |
| GSE43922 | Up | 0.0133557900 |
| GSE24585 | Up | 0.0140202629 |
| GSE37065 | Down | -0.0847256840 |
| GSE28863_A1 | Up | 0.0463112381 |
| GSE28863_A2 | Up | 0.1896408622 |
| GSE28863_A3 | Up | 0.0780551044 |
| GSE28863_A4 | Down | -0.1401250769 |
| GSE48662 | Up | 0.4455905559 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-326 | MIMAT0000756 | MIRT043653 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT051712 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052496 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
