HCSGD entry for AMOTL1
1. General information
| Official gene symbol | AMOTL1 |
|---|---|
| Entrez ID | 154810 |
| Gene full name | angiomotin like 1 |
| Other gene symbols | JEAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003365 | Establishment of cell polarity involved in ameboidal cell migration | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005923 | Tight junction | IDA | cellular_component |
| GO:0008180 | COP9 signalosome | IDA | cellular_component |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0035329 | Hippo signaling | TAS | biological_process |
| GO:0042802 | Identical protein binding | IDA | molecular_function |
| GO:0043536 | Positive regulation of blood vessel endothelial cell migration | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9271453022 | 0.0121404696 | 0.9999902473 | 0.2175284547 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1338492329 |
| GSE13712_SHEAR | Down | -0.3942913952 |
| GSE13712_STATIC | Down | -0.0255519085 |
| GSE19018 | Down | -0.4722306617 |
| GSE19899_A1 | Down | -0.4903192124 |
| GSE19899_A2 | Down | -1.1487726444 |
| PubMed_21979375_A1 | Down | -1.3285596547 |
| PubMed_21979375_A2 | Down | -0.7443182510 |
| GSE35957 | Up | 0.0762990956 |
| GSE36640 | Down | -1.3230810368 |
| GSE54402 | Down | -0.5327783446 |
| GSE9593 | Up | 0.5891660971 |
| GSE43922 | Down | -0.6438341844 |
| GSE24585 | Down | -0.3100568670 |
| GSE37065 | Up | 0.0474185466 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.9229775019 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042034 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046290 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049611 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
