HCSGD entry for IRX2
1. General information
| Official gene symbol | IRX2 |
|---|---|
| Entrez ID | 153572 |
| Gene full name | iroquois homeobox 2 |
| Other gene symbols | IRXA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0072086 | Specification of loop of Henle identity | IEA | biological_process |
| GO:0072272 | Proximal/distal pattern formation involved in metanephric nephron development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7524138407 | 0.3024746210 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0294108195 |
| GSE13712_SHEAR | Down | -0.1459145224 |
| GSE13712_STATIC | Down | -0.2515430764 |
| GSE19018 | Down | -0.3364627560 |
| GSE19899_A1 | Up | 0.0505850673 |
| GSE19899_A2 | Up | 0.2128751233 |
| PubMed_21979375_A1 | Up | 0.1036420814 |
| PubMed_21979375_A2 | Down | -0.0613581477 |
| GSE35957 | Down | -0.2636910738 |
| GSE36640 | Down | -0.5538856702 |
| GSE54402 | Up | 0.0383263171 |
| GSE9593 | Down | -0.2224333980 |
| GSE43922 | Up | 0.2194136740 |
| GSE24585 | Up | 0.0758210361 |
| GSE37065 | Up | 0.0285913690 |
| GSE28863_A1 | Down | -0.1123613357 |
| GSE28863_A2 | Up | 0.0068721020 |
| GSE28863_A3 | Up | 0.2229695155 |
| GSE28863_A4 | Down | -0.0793667839 |
| GSE48662 | Up | 0.1437898153 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017070 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
