HCSGD entry for CXADR

1. General information

Official gene symbolCXADR
Entrez ID1525
Gene full namecoxsackie virus and adenovirus receptor
Other gene symbolsCAR CAR4/6 HCAR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001618Virus receptor activityIEAmolecular_function
GO:0001669Acrosomal vesicleISScellular_component
GO:0005102Receptor bindingIPImolecular_function
GO:0005178Integrin bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0005912Adherens junctionIDAcellular_component
GO:0005923Tight junctionIDAcellular_component
GO:0007005Mitochondrion organizationISSbiological_process
GO:0007157Heterophilic cell-cell adhesionIDAbiological_process
GO:0007507Heart developmentISSbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008013Beta-catenin bindingIPImolecular_function
GO:0008354Germ cell migrationISSbiological_process
GO:0010669Epithelial structure maintenanceIMPbiological_process
GO:0014704Intercalated discIDA IEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016327Apicolateral plasma membraneIDAcellular_component
GO:0030054Cell junctionIDAcellular_component
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030175FilopodiumISScellular_component
GO:0030426Growth coneISScellular_component
GO:0030593Neutrophil chemotaxisIMPbiological_process
GO:0031532Actin cytoskeleton reorganizationIDAbiological_process
GO:0031594Neuromuscular junctionIDAcellular_component
GO:0034109Homotypic cell-cell adhesionIDAbiological_process
GO:0042802Identical protein bindingIDAmolecular_function
GO:0043005Neuron projectionISScellular_component
GO:0043234Protein complexIDAcellular_component
GO:0044297Cell bodyISScellular_component
GO:0045121Membrane raftIDAcellular_component
GO:0045216Cell-cell junction organizationISSbiological_process
GO:0046629Gamma-delta T cell activationISSbiological_process
GO:0048739Cardiac muscle fiber developmentISSbiological_process
GO:0050776Regulation of immune responseTASbiological_process
GO:0050839Cell adhesion molecule bindingIPImolecular_function
GO:0050900Leukocyte migrationTASbiological_process
GO:0051607Defense response to virusIDAbiological_process
GO:0060044Negative regulation of cardiac muscle cell proliferationIEAbiological_process
GO:0070633Transepithelial transportIMPbiological_process
GO:0071253Connexin bindingISSmolecular_function
GO:0086067AV node cell to bundle of His cell communicationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00085298050.99067830250.08076007191.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3318743797
GSE13712_SHEARUp0.3570732474
GSE13712_STATICUp0.4522009266
GSE19018Up0.2569714886
GSE19899_A1Up0.6685438349
GSE19899_A2Up2.6219739508
PubMed_21979375_A1Up2.4102430959
PubMed_21979375_A2Up2.6351550246
GSE35957Up0.1744328985
GSE36640Up0.5550047561
GSE54402Up0.0609109603
GSE9593Down-0.0867268321
GSE43922Up2.6524145028
GSE24585Up0.0920653984
GSE37065Down-0.0752824468
GSE28863_A1Up0.2874746605
GSE28863_A2Down-0.1963393010
GSE28863_A3Up0.5730610525
GSE28863_A4Up0.1481939477
GSE48662Down-0.0153229997

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT020061MicroarrayFunctional MTI (Weak)20215506
hsa-miR-26b-5pMIMAT0000083MIRT030352MicroarrayFunctional MTI (Weak)19088304
hsa-miR-296-3pMIMAT0004679MIRT038505CLASHFunctional MTI (Weak)23622248
hsa-miR-342-3pMIMAT0000753MIRT043740CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.