HCSGD entry for FGD5

1. General information

Official gene symbolFGD5
Entrez ID152273
Gene full nameFYVE, RhoGEF and PH domain containing 5
Other gene symbolsZFYVE23
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleISScellular_component
GO:0005085Guanyl-nucleotide exchange factor activityISSmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005769Early endosomeIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0007010Cytoskeleton organizationISSbiological_process
GO:0008360Regulation of cell shapeISSbiological_process
GO:0030027LamellipodiumISScellular_component
GO:0030036Actin cytoskeleton organizationISSbiological_process
GO:0031267Small GTPase bindingISSmolecular_function
GO:0032587Ruffle membraneIEAcellular_component
GO:0043088Regulation of Cdc42 GTPase activityISSbiological_process
GO:0046847Filopodium assemblyISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46291859730.78192373770.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0748611656
GSE13712_SHEARDown-0.2559301638
GSE13712_STATICDown-0.1493053771
GSE19018Up0.0566124668
GSE19899_A1Up0.0191886210
GSE19899_A2Down-0.0420167735
PubMed_21979375_A1Up0.0755344595
PubMed_21979375_A2Down-0.1195221449
GSE35957Up0.1715075901
GSE36640Up0.0519923692
GSE54402Up0.0708650237
GSE9593Up0.0292848625
GSE43922Up0.0294383065
GSE24585Down-0.0698179089
GSE37065Down-0.1267008413
GSE28863_A1Down-0.0584251527
GSE28863_A2Up0.2686723930
GSE28863_A3Up0.4588004158
GSE28863_A4Up0.0586423595
GSE48662Down-0.0227513414

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.