HCSGD entry for PPP4R2
1. General information
| Official gene symbol | PPP4R2 |
|---|---|
| Entrez ID | 151987 |
| Gene full name | protein phosphatase 4, regulatory subunit 2 |
| Other gene symbols | PP4R2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005813 | Centrosome | TAS | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0010569 | Regulation of double-strand break repair via homologous recombination | IMP | biological_process |
| GO:0030289 | Protein phosphatase 4 complex | IDA | cellular_component |
| GO:0030362 | Protein phosphatase type 4 regulator activity | IMP | molecular_function |
| GO:0030674 | Protein binding, bridging | IMP | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1061514988 | 0.8323734775 | 0.6766804553 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0034054774 |
| GSE13712_SHEAR | Up | 0.3861835285 |
| GSE13712_STATIC | Down | -0.1419165321 |
| GSE19018 | Down | -0.0605840657 |
| GSE19899_A1 | Up | 0.3786419492 |
| GSE19899_A2 | Up | 0.1598650116 |
| PubMed_21979375_A1 | Up | 0.5919965048 |
| PubMed_21979375_A2 | Up | 0.3054642655 |
| GSE35957 | Down | -0.1106928048 |
| GSE36640 | Up | 0.1664936408 |
| GSE54402 | Up | 0.1174394378 |
| GSE9593 | Down | -0.0960551462 |
| GSE43922 | Up | 0.3483686621 |
| GSE24585 | Down | -0.0010843536 |
| GSE37065 | Up | 0.0951621384 |
| GSE28863_A1 | Up | 0.1204333663 |
| GSE28863_A2 | Down | -0.1245216277 |
| GSE28863_A3 | Down | -0.1264561757 |
| GSE28863_A4 | Up | 0.0683362480 |
| GSE48662 | Up | 0.1146449276 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021467 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044944 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
