HCSGD entry for UPP2

1. General information

Official gene symbolUPP2
Entrez ID151531
Gene full nameuridine phosphorylase 2
Other gene symbolsUDRPASE2 UP2 UPASE2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004850Uridine phosphorylase activityIDAmolecular_function
GO:0005829CytosolNAS TAScellular_component
GO:0006206Pyrimidine nucleobase metabolic processTASbiological_process
GO:0009116Nucleoside metabolic processNASbiological_process
GO:0009166Nucleotide catabolic processIEAbiological_process
GO:0043097Pyrimidine nucleoside salvageTASbiological_process
GO:0044206UMP salvageIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045098Type III intermediate filamentIDAcellular_component
GO:0046108Uridine metabolic processNASbiological_process
GO:0046135Pyrimidine nucleoside catabolic processTASbiological_process
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82132948980.82265363020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1107098062
GSE13712_SHEARDown-0.1246939218
GSE13712_STATICDown-0.0340462496
GSE19018Up0.0408168533
GSE19899_A1Down-0.0267539572
GSE19899_A2Down-0.0500892062
PubMed_21979375_A1Up0.0758340567
PubMed_21979375_A2Up0.1192438125
GSE35957Up0.0662231440
GSE36640Up0.0614556991
GSE54402Down-0.1427036592
GSE9593Up0.1407618871
GSE43922Up0.0104826877
GSE24585Down-0.0638505624
GSE37065Down-0.0046227937
GSE28863_A1Down-0.0187117615
GSE28863_A2Up0.0188626414
GSE28863_A3Up0.0716596038
GSE28863_A4Up0.0574630271
GSE48662Up0.0109465065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

RP101DB05041 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7a-5pMIMAT0000062MIRT052364CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.