HCSGD entry for GDF7


1. General information

Official gene symbolGDF7
Entrez ID151449
Gene full namegrowth differentiation factor 7
Other gene symbolsBMP12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0007411Axon guidanceIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0010862Positive regulation of pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:0021509Roof plate formationIEAbiological_process
GO:0021527Spinal cord association neuron differentiationIEAbiological_process
GO:0022612Gland morphogenesisIEAbiological_process
GO:0030509BMP signaling pathwayIDAbiological_process
GO:0030855Epithelial cell differentiationIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0032924Activin receptor signaling pathwayIDAbiological_process
GO:0040007GrowthIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045165Cell fate commitmentIEAbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0048608Reproductive structure developmentIEAbiological_process
GO:0048754Branching morphogenesis of an epithelial tubeIEAbiological_process
GO:0048853Forebrain morphogenesisIEAbiological_process
GO:0060389Pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:0060571Morphogenesis of an epithelial foldIEAbiological_process
GO:2001051Positive regulation of tendon cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26797799100.97278261460.96515862641.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1439701942
GSE24585Down-0.0501253992
GSE37065Down-0.0637812994
GSE28863_A1Down-0.1633267521
GSE28863_A2Up0.1925884691
GSE28863_A3Up0.3377028664
GSE28863_A4Up0.1596781281
GSE48662Up0.3752623855

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-197-3pMIMAT0000227MIRT048114CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.