HCSGD entry for GPBAR1
1. General information
| Official gene symbol | GPBAR1 |
|---|---|
| Entrez ID | 151306 |
| Gene full name | G protein-coupled bile acid receptor 1 |
| Other gene symbols | BG37 GPCR19 GPR131 M-BAR TGR5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0038181 | Bile acid receptor activity | IDA | molecular_function |
| GO:0038182 | G-protein coupled bile acid receptor activity | NAS | molecular_function |
| GO:0038184 | Cell surface bile acid receptor signaling pathway | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5392514988 | 0.8133593974 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0569752769 |
| GSE13712_SHEAR | Up | 0.0535518101 |
| GSE13712_STATIC | Up | 0.0650625609 |
| GSE19018 | Up | 0.0019313538 |
| GSE19899_A1 | Down | -0.0509063069 |
| GSE19899_A2 | Up | 0.1971495685 |
| PubMed_21979375_A1 | Down | -0.2632390915 |
| PubMed_21979375_A2 | Down | -0.1120169127 |
| GSE35957 | Down | -0.0009356941 |
| GSE36640 | Up | 0.1631385489 |
| GSE54402 | Up | 0.0123139727 |
| GSE9593 | Up | 0.0769756476 |
| GSE43922 | Up | 0.0996963883 |
| GSE24585 | Down | -0.0729306020 |
| GSE37065 | Down | -0.1277805137 |
| GSE28863_A1 | Down | -0.0594486480 |
| GSE28863_A2 | Up | 0.0648400610 |
| GSE28863_A3 | Up | 0.2045144471 |
| GSE28863_A4 | Up | 0.2720674121 |
| GSE48662 | Down | -0.0179690603 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017548 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
