HCSGD entry for COMMD1
1. General information
| Official gene symbol | COMMD1 |
|---|---|
| Entrez ID | 150684 |
| Gene full name | copper metabolism (Murr1) domain containing 1 |
| Other gene symbols | C2orf5 MURR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005507 | Copper ion binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0031398 | Positive regulation of protein ubiquitination | IDA | biological_process |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IDA IMP | biological_process |
| GO:0032434 | Regulation of proteasomal ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0055070 | Copper ion homeostasis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8125192394 | 0.4811722465 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1987109722 |
| GSE13712_SHEAR | Down | -0.1836002183 |
| GSE13712_STATIC | Down | -0.1577051861 |
| GSE19018 | Up | 0.0285034119 |
| GSE19899_A1 | Down | -0.0280608844 |
| GSE19899_A2 | Up | 0.1821038480 |
| PubMed_21979375_A1 | Up | 0.7909365679 |
| PubMed_21979375_A2 | Down | -0.0113474334 |
| GSE35957 | Down | -0.3271722608 |
| GSE36640 | Up | 0.1478373242 |
| GSE54402 | Down | -0.0101934032 |
| GSE9593 | Up | 0.1128683291 |
| GSE43922 | Down | -0.0500280385 |
| GSE24585 | Down | -0.0164671929 |
| GSE37065 | Down | -0.1359303991 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2797351872 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
