HCSGD entry for TTL
1. General information
| Official gene symbol | TTL |
|---|---|
| Entrez ID | 150465 |
| Gene full name | tubulin tyrosine ligase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0004835 | Tubulin-tyrosine ligase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006464 | Cellular protein modification process | IEA | biological_process |
| GO:0030516 | Regulation of axon extension | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0640231070 | 0.7132509175 | 0.5451347671 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3550560283 |
| GSE13712_SHEAR | Down | -0.0506825437 |
| GSE13712_STATIC | Down | -0.0598981706 |
| GSE19018 | Down | -0.3891936097 |
| GSE19899_A1 | Up | 0.5518232481 |
| GSE19899_A2 | Up | 0.3206967339 |
| PubMed_21979375_A1 | Up | 1.1937442068 |
| PubMed_21979375_A2 | Up | 0.5084499550 |
| GSE35957 | Down | -0.0467516654 |
| GSE36640 | Down | -0.0791672220 |
| GSE54402 | Up | 0.6850191117 |
| GSE9593 | Up | 0.1117027018 |
| GSE43922 | Up | 0.7557069992 |
| GSE24585 | Down | -0.0504132690 |
| GSE37065 | Down | -0.0658907633 |
| GSE28863_A1 | Down | -0.2724702634 |
| GSE28863_A2 | Up | 0.0221146103 |
| GSE28863_A3 | Down | -0.1795625857 |
| GSE28863_A4 | Down | -0.1581544160 |
| GSE48662 | Down | -0.2311022880 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320c | MIMAT0005793 | MIRT036172 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036928 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038458 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045574 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049681 | CLASH | Functional MTI (Weak) | 23622248 |
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