HCSGD entry for RNF187
1. General information
| Official gene symbol | RNF187 |
|---|---|
| Entrez ID | 149603 |
| Gene full name | ring finger protein 187 |
| Other gene symbols | RACO-1 RACO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008284 | Positive regulation of cell proliferation | ISS | biological_process |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IMP | biological_process |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2217340261 | 0.8890102276 | 0.9031558460 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1097369977 |
| GSE13712_SHEAR | Down | -0.1070074653 |
| GSE13712_STATIC | Down | -0.2080138936 |
| GSE19018 | Up | 0.3282215675 |
| GSE19899_A1 | Up | 0.1064412588 |
| GSE19899_A2 | Up | 0.3898516632 |
| PubMed_21979375_A1 | Down | -0.0645943716 |
| PubMed_21979375_A2 | Up | 0.2787493501 |
| GSE35957 | Up | 0.1062550212 |
| GSE36640 | Up | 0.3227349792 |
| GSE54402 | Up | 0.0265479561 |
| GSE9593 | Up | 0.1395787433 |
| GSE43922 | Up | 0.1543569608 |
| GSE24585 | Down | -0.2015390756 |
| GSE37065 | Down | -0.2198502134 |
| GSE28863_A1 | Up | 0.0883423487 |
| GSE28863_A2 | Up | 0.3238507688 |
| GSE28863_A3 | Up | 0.0338423368 |
| GSE28863_A4 | Down | -0.1536897906 |
| GSE48662 | Up | 0.6005516262 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029670 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040880 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047251 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048702 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
