HCSGD entry for IL23R


1. General information

Official gene symbolIL23R
Entrez ID149233
Gene full nameinterleukin 23 receptor
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001916Positive regulation of T cell mediated cytotoxicityISSbiological_process
GO:0002230Positive regulation of defense response to virus by hostIDA ISSbiological_process
GO:0002827Positive regulation of T-helper 1 type immune responseIDA ISSbiological_process
GO:0005143Interleukin-12 receptor bindingIPImolecular_function
GO:0006954Inflammatory responseIEAbiological_process
GO:0007165Signal transductionIDAbiological_process
GO:0010535Positive regulation of activation of JAK2 kinase activityICbiological_process
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0032496Response to lipopolysaccharideIDAbiological_process
GO:0032693Negative regulation of interleukin-10 productionIMPbiological_process
GO:0032725Positive regulation of granulocyte macrophage colony-stimulating factor productionICbiological_process
GO:0032729Positive regulation of interferon-gamma productionIC IDA TASbiological_process
GO:0032735Positive regulation of interleukin-12 productionIDAbiological_process
GO:0032740Positive regulation of interleukin-17 productionICbiological_process
GO:0032819Positive regulation of natural killer cell proliferationICbiological_process
GO:0034341Response to interferon-gammaIDAbiological_process
GO:0038155Interleukin-23-mediated signaling pathwayIDAbiological_process
GO:0042019Interleukin-23 bindingIPImolecular_function
GO:0042020Interleukin-23 receptor activityIDAmolecular_function
GO:0042102Positive regulation of T cell proliferationICbiological_process
GO:0042104Positive regulation of activated T cell proliferationICbiological_process
GO:0042510Regulation of tyrosine phosphorylation of Stat1 proteinICbiological_process
GO:0042517Positive regulation of tyrosine phosphorylation of Stat3 proteinICbiological_process
GO:0042520Positive regulation of tyrosine phosphorylation of Stat4 proteinICbiological_process
GO:0042523Positive regulation of tyrosine phosphorylation of Stat5 proteinICbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0043382Positive regulation of memory T cell differentiationISSbiological_process
GO:0045672Positive regulation of osteoclast differentiationICbiological_process
GO:0050829Defense response to Gram-negative bacteriumICbiological_process
GO:0051135Positive regulation of NK T cell activationICbiological_process
GO:0072536Interleukin-23 receptor complexIDAcellular_component
GO:2000318Positive regulation of T-helper 17 type immune responseISSbiological_process
GO:2000330Positive regulation of T-helper 17 cell lineage commitmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91009036510.59191480950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1377318909
GSE13712_SHEARUp0.0606645882
GSE13712_STATICDown-0.0982838746
GSE19018Up0.0861867260
GSE19899_A1Up0.0044405011
GSE19899_A2Up0.1595545027
PubMed_21979375_A1Up0.0526906004
PubMed_21979375_A2Up0.0328549874
GSE35957Down-0.0780418376
GSE36640Up0.0201408873
GSE54402Up0.0169667948
GSE9593Down-0.0780965269
GSE43922Up0.0217016517
GSE24585Down-0.0523375208
GSE37065Down-0.0024640278
GSE28863_A1Down-0.2297631732
GSE28863_A2Down-0.1741277698
GSE28863_A3Up0.0462942771
GSE28863_A4Down-0.1154789636
GSE48662Down-0.1114321402

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.