HCSGD entry for SIX5


1. General information

Official gene symbolSIX5
Entrez ID147912
Gene full nameSIX homeobox 5
Other gene symbolsBOR2 DMAHP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002088Lens development in camera-type eyeIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007286Spermatid developmentIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41940746170.83226395650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0229420467
GSE13712_SHEARDown-0.1773492554
GSE13712_STATICDown-0.0076946154
GSE19018Down-0.0397550773
GSE19899_A1Down-0.0729864926
GSE19899_A2Up0.3109361019
PubMed_21979375_A1Up0.0338313772
PubMed_21979375_A2Up0.4717542409
GSE35957Up0.0139496331
GSE36640Up0.0418143081
GSE54402Up0.0371675022
GSE9593Up0.0268767403
GSE43922Up0.0527975594
GSE24585Up0.1766282133
GSE37065Down-0.2041646087
GSE28863_A1Up0.1399045687
GSE28863_A2Down-0.1979821717
GSE28863_A3Up0.2890644445
GSE28863_A4Down-0.0349273380
GSE48662Up0.3904730769

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029180MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.