HCSGD entry for TMC8
1. General information
| Official gene symbol | TMC8 |
|---|---|
| Entrez ID | 147138 |
| Gene full name | transmembrane channel-like 8 |
| Other gene symbols | EV2 EVER2 EVIN2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006811 | Ion transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4840895559 | 0.8160857186 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0878051338 |
| GSE13712_SHEAR | Down | -0.2813676952 |
| GSE13712_STATIC | Down | -0.0436689552 |
| GSE19018 | Up | 0.2795992632 |
| GSE19899_A1 | Down | -0.0001627854 |
| GSE19899_A2 | Up | 0.0663370116 |
| PubMed_21979375_A1 | Down | -0.0038376637 |
| PubMed_21979375_A2 | Up | 0.0187373736 |
| GSE35957 | Up | 0.1914753255 |
| GSE36640 | Down | -0.0169470042 |
| GSE54402 | Up | 0.0681875225 |
| GSE9593 | Down | -0.0604445975 |
| GSE43922 | Up | 0.1135289667 |
| GSE24585 | Up | 0.1308966714 |
| GSE37065 | Down | -0.0473952413 |
| GSE28863_A1 | Down | -0.2120034097 |
| GSE28863_A2 | Down | -0.1953586726 |
| GSE28863_A3 | Up | 0.4360681286 |
| GSE28863_A4 | Up | 0.1503389027 |
| GSE48662 | Down | -0.0648144042 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016489 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018436 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
