HCSGD entry for ADRA1B

1. General information

Official gene symbolADRA1B
Entrez ID147
Gene full nameadrenoceptor alpha 1B
Other gene symbolsADRA1 ALPHA1BAR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001974Blood vessel remodelingIEAbiological_process
GO:0001975Response to amphetamineIEAbiological_process
GO:0001987Vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressureIEAbiological_process
GO:0001996Positive regulation of heart rate by epinephrine-norepinephrineIEAbiological_process
GO:0001997Positive regulation of the force of heart contraction by epinephrine-norepinephrineIEAbiological_process
GO:0004937Alpha1-adrenergic receptor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007512Adult heart developmentIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008542Visual learningIEAbiological_process
GO:0016049Cell growthIEAbiological_process
GO:0019229Regulation of vasoconstrictionIEAbiological_process
GO:0031965Nuclear membraneIDAcellular_component
GO:0035265Organ growthIEAbiological_process
GO:0035556Intracellular signal transductionTASbiological_process
GO:0042593Glucose homeostasisIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0043410Positive regulation of MAPK cascadeIDAbiological_process
GO:0045818Negative regulation of glycogen catabolic processIEAbiological_process
GO:0045819Positive regulation of glycogen catabolic processIEAbiological_process
GO:0046982Protein heterodimerization activityIDAmolecular_function
GO:0048148Behavioral response to cocaineIEAbiological_process
GO:0055117Regulation of cardiac muscle contractionIEAbiological_process
GO:0071875Adrenergic receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86912998370.32481723720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1326862632
GSE13712_SHEARUp0.1026703800
GSE13712_STATICUp0.0144050216
GSE19018Down-0.1480317828
GSE19899_A1Down-0.1642651236
GSE19899_A2Down-0.0613809053
PubMed_21979375_A1Up0.1992767083
PubMed_21979375_A2Up0.1294322719
GSE35957Up0.1217217995
GSE36640Down-0.1380278252
GSE54402Up0.0318871187
GSE9593Down-0.1577087805
GSE43922Down-0.3731983600
GSE24585Up0.2184362248
GSE37065Down-0.1190456540
GSE28863_A1Down-0.2150715050
GSE28863_A2Down-0.0244540584
GSE28863_A3Up0.0802381382
GSE28863_A4Up0.0413072388
GSE48662Down-0.2592486793

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-10b-5pMIMAT0000254MIRT047408CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.