HCSGD entry for NCAN
1. General information
| Official gene symbol | NCAN |
|---|---|
| Entrez ID | 1463 |
| Gene full name | neurocan |
| Other gene symbols | CSPG3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005540 | Hyaluronic acid binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030204 | Chondroitin sulfate metabolic process | TAS | biological_process |
| GO:0030206 | Chondroitin sulfate biosynthetic process | TAS | biological_process |
| GO:0030207 | Chondroitin sulfate catabolic process | TAS | biological_process |
| GO:0030208 | Dermatan sulfate biosynthetic process | TAS | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051823 | Regulation of synapse structural plasticity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5006850652 | 0.8535552373 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0087476411 |
| GSE13712_SHEAR | Down | -0.1003940511 |
| GSE13712_STATIC | Down | -0.0440110307 |
| GSE19018 | Up | 0.1047589462 |
| GSE19899_A1 | Up | 0.0132052222 |
| GSE19899_A2 | Up | 0.3671133257 |
| PubMed_21979375_A1 | Down | -0.0756427570 |
| PubMed_21979375_A2 | Down | -0.2632382845 |
| GSE35957 | Up | 0.0467001955 |
| GSE36640 | Up | 0.1496224474 |
| GSE54402 | Down | -0.0022054484 |
| GSE9593 | Down | -0.0124416965 |
| GSE43922 | Up | 0.1072330930 |
| GSE24585 | Up | 0.0883642646 |
| GSE37065 | Up | 0.0113279318 |
| GSE28863_A1 | Down | -0.2089585994 |
| GSE28863_A2 | Down | -0.1426222445 |
| GSE28863_A3 | Up | 0.3641664596 |
| GSE28863_A4 | Up | 0.1311907997 |
| GSE48662 | Up | 0.2671188177 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
| Thiodigalactoside | DB04396 | EXPT03030 |
| Hyaluronic acid | DB08818 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-342-3p | MIMAT0000753 | MIRT043672 | CLASH | Functional MTI (Weak) | 23622248 |
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