HCSGD entry for TTBK2
1. General information
| Official gene symbol | TTBK2 |
|---|---|
| Entrez ID | 146057 |
| Gene full name | tau tubulin kinase 2 |
| Other gene symbols | SCA11 TTBK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005814 | Centriole | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0007224 | Smoothened signaling pathway | IEA ISS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0018105 | Peptidyl-serine phosphorylation | IDA | biological_process |
| GO:0035869 | Ciliary transition zone | IEA ISS | cellular_component |
| GO:0036064 | Ciliary basal body | IEA ISS | cellular_component |
| GO:0042384 | Cilium assembly | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5550526310 | 0.4600748414 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0441929430 |
| GSE13712_SHEAR | Up | 0.0438947026 |
| GSE13712_STATIC | Up | 0.0604640690 |
| GSE19018 | Up | 0.3406599306 |
| GSE19899_A1 | Up | 0.0710351346 |
| GSE19899_A2 | Down | -0.2636076974 |
| PubMed_21979375_A1 | Down | -0.5356576723 |
| PubMed_21979375_A2 | Down | -0.1776760137 |
| GSE35957 | Down | -0.0781731080 |
| GSE36640 | Down | -0.1527933506 |
| GSE54402 | Down | -0.2393475586 |
| GSE9593 | Down | -0.0052534381 |
| GSE43922 | Down | -0.2017564540 |
| GSE24585 | Up | 0.3756384277 |
| GSE37065 | Down | -0.0513733521 |
| GSE28863_A1 | Up | 0.3411872063 |
| GSE28863_A2 | Up | 0.3349586215 |
| GSE28863_A3 | Down | -0.2193640627 |
| GSE28863_A4 | Down | -0.0698018679 |
| GSE48662 | Up | 0.4162530934 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
