HCSGD entry for BEST3
1. General information
| Official gene symbol | BEST3 |
|---|---|
| Entrez ID | 144453 |
| Gene full name | bestrophin 3 |
| Other gene symbols | VMD2L3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005254 | Chloride channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0034707 | Chloride channel complex | IEA | cellular_component |
| GO:0043271 | Negative regulation of ion transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2031642491 | 0.9660317769 | 0.8701306816 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0342752770 |
| GSE13712_SHEAR | Down | -0.0310623060 |
| GSE13712_STATIC | Up | 0.1293201583 |
| GSE19018 | Up | 0.0555801501 |
| GSE19899_A1 | Up | 0.1155336217 |
| GSE19899_A2 | Up | 0.2837246784 |
| PubMed_21979375_A1 | Up | 0.1909750720 |
| PubMed_21979375_A2 | Up | 0.1682374588 |
| GSE35957 | Down | -0.0255045647 |
| GSE36640 | Up | 0.4219673464 |
| GSE54402 | Up | 0.4335966123 |
| GSE9593 | Down | -0.0775210567 |
| GSE43922 | Up | 0.2274573773 |
| GSE24585 | Up | 0.0449845143 |
| GSE37065 | Up | 0.0322623509 |
| GSE28863_A1 | Down | -0.0198137166 |
| GSE28863_A2 | Down | -0.1217668194 |
| GSE28863_A3 | Up | 0.0684431479 |
| GSE28863_A4 | Down | -0.0607349005 |
| GSE48662 | Up | 0.4139577544 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042669 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
