HCSGD entry for CSF2RB


1. General information

Official gene symbolCSF2RB
Entrez ID1439
Gene full namecolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Other gene symbolsCD131 CDw131 IL3RB IL5RB SMDP5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityTASmolecular_function
GO:0004896Cytokine receptor activityIEAmolecular_function
GO:0004912Interleukin-3 receptor activityTASmolecular_function
GO:0004914Interleukin-5 receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0007165Signal transductionNASbiological_process
GO:0007585Respiratory gaseous exchangeTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030526Granulocyte macrophage colony-stimulating factor receptor complexTAScellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0036016Cellular response to interleukin-3TASbiological_process
GO:0038043Interleukin-5-mediated signaling pathwayTASbiological_process
GO:0038156Interleukin-3-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07768484480.03720271650.58807673280.3635729499

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.1504193893
GSE13712_SHEARDown-0.2524968912
GSE13712_STATICUp0.1787523377
GSE19018Up0.0476690178
GSE19899_A1Up0.2735967482
GSE19899_A2Up0.1055371903
PubMed_21979375_A1Up0.0563180849
PubMed_21979375_A2Down-0.1737867382
GSE35957Up4.2898820246
GSE36640Up2.1184843408
GSE54402Down-0.0339425296
GSE9593Up0.1103335421
GSE43922Up0.0275441049
GSE24585Up0.1298263821
GSE37065Down-0.0570412499
GSE28863_A1Down-2.6345758952
GSE28863_A2Down-0.2778477005
GSE28863_A3Down-0.4084651816
GSE28863_A4Up0.0691397338
GSE48662Up0.0162556154

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

SargramostimDB00020 BTD00035 | BIOD00035
NPI 32101DB05264 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.