HCSGD entry for PIWIL4


1. General information

Official gene symbolPIWIL4
Entrez ID143689
Gene full namepiwi-like RNA-mediated gene silencing 4
Other gene symbolsHIWI2 MIWI2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005634NucleusIEA ISScellular_component
GO:0005737CytoplasmISScellular_component
GO:0006417Regulation of translationIEAbiological_process
GO:0007126MeiosisIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisIEA ISSbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0031047Gene silencing by RNAIEA ISSbiological_process
GO:0034584PiRNA bindingIEA ISSmolecular_function
GO:0034587PiRNA metabolic processIEA ISSbiological_process
GO:0043046DNA methylation involved in gamete generationIEA ISSbiological_process
GO:0043186P granuleISScellular_component
GO:0071547PiP-bodyIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09418108350.81428101520.64287870851.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3127996655
GSE13712_SHEARUp0.2131501626
GSE13712_STATICUp0.1233445457
GSE19018Up0.2231088786
GSE19899_A1Up0.1077732084
GSE19899_A2Up0.0542869427
PubMed_21979375_A1Up0.3150748137
PubMed_21979375_A2Down-0.0872971168
GSE35957Down-0.6178115024
GSE36640Up0.5648810081
GSE54402Up0.4520660294
GSE9593Down-0.4707921426
GSE43922Up0.0134676059
GSE24585Down-0.0645511969
GSE37065Up0.4442580594
GSE28863_A1Up0.2816286175
GSE28863_A2Up0.5928644129
GSE28863_A3Down-0.0998271045
GSE28863_A4Down-0.0780216304
GSE48662Up0.1253362365

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018636MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT023027MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.