HCSGD entry for SESN3
1. General information
| Official gene symbol | SESN3 |
|---|---|
| Entrez ID | 143686 |
| Gene full name | sestrin 3 |
| Other gene symbols | SEST3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007050 | Cell cycle arrest | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6470143612 | 0.0108913681 | 0.9999902473 | 0.2064739568 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0473054109 |
| GSE13712_SHEAR | Down | -1.2216810717 |
| GSE13712_STATIC | Down | -1.1822830606 |
| GSE19018 | Down | -0.2137636718 |
| GSE19899_A1 | Up | 0.0427728416 |
| GSE19899_A2 | Down | -0.6518704711 |
| PubMed_21979375_A1 | Down | -0.9725912198 |
| PubMed_21979375_A2 | Down | -0.3371561724 |
| GSE35957 | Down | -0.0065488539 |
| GSE36640 | Up | 1.1245159863 |
| GSE54402 | Down | -1.1242854238 |
| GSE9593 | Down | -0.1212939660 |
| GSE43922 | Down | -0.8998726852 |
| GSE24585 | Up | 0.0794797539 |
| GSE37065 | Down | -0.1115214251 |
| GSE28863_A1 | Up | 0.8785643590 |
| GSE28863_A2 | Up | 0.1484642564 |
| GSE28863_A3 | Down | -0.7315966516 |
| GSE28863_A4 | Up | 0.1141034586 |
| GSE48662 | Up | 0.3016038654 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016230 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017124 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
