HCSGD entry for SRXN1
1. General information
| Official gene symbol | SRXN1 |
|---|---|
| Entrez ID | 140809 |
| Gene full name | sulfiredoxin 1 |
| Other gene symbols | C20orf139 Npn3 SRX SRX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006979 | Response to oxidative stress | IDA | biological_process |
| GO:0016667 | Oxidoreductase activity, acting on a sulfur group of donors | IDA | molecular_function |
| GO:0032542 | Sulfiredoxin activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0051937958 | 0.8844662589 | 0.1880411279 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9562196248 |
| GSE13712_SHEAR | Up | 0.1747985352 |
| GSE13712_STATIC | Up | 0.6281866461 |
| GSE19018 | Down | -0.6340837881 |
| GSE19899_A1 | Up | 0.4878854137 |
| GSE19899_A2 | Up | 0.6159474700 |
| PubMed_21979375_A1 | Up | 1.2523996858 |
| PubMed_21979375_A2 | Up | 1.4213493195 |
| GSE35957 | Up | 0.0233552751 |
| GSE36640 | Up | 0.7588037703 |
| GSE54402 | Up | 0.8347190367 |
| GSE9593 | Up | 0.8132505603 |
| GSE43922 | Up | 0.7854095744 |
| GSE24585 | Down | -0.7317565486 |
| GSE37065 | Up | 0.1508784511 |
| GSE28863_A1 | Down | -0.0712940999 |
| GSE28863_A2 | Up | 0.0055499764 |
| GSE28863_A3 | Down | -0.2518238275 |
| GSE28863_A4 | Down | -0.0278591065 |
| GSE48662 | Down | -0.0507330992 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT003772 | Luciferase reporter assay//Microarray | Functional MTI (WeaK) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT003772 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027877 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
