HCSGD entry for NEK7
1. General information
| Official gene symbol | NEK7 |
|---|---|
| Entrez ID | 140609 |
| Gene full name | NIMA-related kinase 7 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | TAS | biological_process |
| GO:0000922 | Spindle pole | IEA | cellular_component |
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0007346 | Regulation of mitotic cell cycle | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051225 | Spindle assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7688842217 | 0.0406575738 | 0.9999902473 | 0.3802230387 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4419868708 |
| GSE13712_SHEAR | Down | -0.0395723936 |
| GSE13712_STATIC | Up | 0.1196750864 |
| GSE19018 | Down | -0.0404547075 |
| GSE19899_A1 | Down | -0.0212428846 |
| GSE19899_A2 | Down | -0.3553545281 |
| PubMed_21979375_A1 | Down | -0.3970167112 |
| PubMed_21979375_A2 | Down | -0.3205976329 |
| GSE35957 | Up | 0.4712484683 |
| GSE36640 | Down | -0.0458653567 |
| GSE54402 | Down | -0.3831200090 |
| GSE9593 | Up | 0.1739887201 |
| GSE43922 | Down | -0.0297994053 |
| GSE24585 | Up | 0.4803832873 |
| GSE37065 | Down | -0.0505695330 |
| GSE28863_A1 | Down | -0.4229080162 |
| GSE28863_A2 | Down | -0.4058132557 |
| GSE28863_A3 | Down | -0.5876553588 |
| GSE28863_A4 | Down | -0.2517671587 |
| GSE48662 | Up | 0.6366051105 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019647 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027390 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047478 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047638 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
