HCSGD entry for CRX

1. General information

Official gene symbolCRX
Entrez ID1406
Gene full namecone-rod homeobox
Other gene symbolsCORD2 CRD LCA7 OTX3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0009887Organ morphogenesisTASbiological_process
GO:0043522Leucine zipper domain bindingIPImolecular_function
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046534Positive regulation of photoreceptor cell differentiationIEAbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49623105130.74540770870.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0184350439
GSE13712_SHEARUp0.1315482817
GSE13712_STATICUp0.0586480727
GSE19018Up0.1574643817
GSE19899_A1Down-0.0176116926
GSE19899_A2Up0.0301145327
PubMed_21979375_A1Down-0.0988780791
PubMed_21979375_A2Down-0.1463952694
GSE35957Up0.0202872253
GSE36640Up0.0261546408
GSE54402Down-0.0068100710
GSE9593Down-0.0052457674
GSE43922Up0.0088629552
GSE24585Up0.0416735015
GSE37065Down-0.0236050907
GSE28863_A1Down-0.4060383192
GSE28863_A2Up0.0089453185
GSE28863_A3Up0.4856110655
GSE28863_A4Up0.2896401155
GSE48662Up0.1866238759

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.