HCSGD entry for DOCK11


1. General information

Official gene symbolDOCK11
Entrez ID139818
Gene full namededicator of cytokinesis 11
Other gene symbolsACG ZIZ2 bB128O4.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0017048Rho GTPase bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92235853120.01239214320.99999024730.2196455219

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4099611686
GSE13712_SHEARDown-0.3466652473
GSE13712_STATICDown-0.1555112276
GSE19018Up0.0325299916
GSE19899_A1Down-0.3832174054
GSE19899_A2Down-0.6435186960
PubMed_21979375_A1Down-1.7361175160
PubMed_21979375_A2Down-0.6219290007
GSE35957Up0.0807737519
GSE36640Down-1.0089154826
GSE54402Down-0.5444332084
GSE9593Down-0.2642514901
GSE43922Down-0.7262358348
GSE24585Down-0.1054633284
GSE37065Down-0.0757386186
GSE28863_A1Up0.7508927378
GSE28863_A2Up0.5354259047
GSE28863_A3Up0.0074229289
GSE28863_A4Up0.0847441314
GSE48662Down-0.0758762652

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018377MicroarrayFunctional MTI (Weak)18185580
hsa-miR-92b-3pMIMAT0003218MIRT040608CLASHFunctional MTI (Weak)23622248
hsa-miR-99a-5pMIMAT0000097MIRT048666CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.