HCSGD entry for DOCK11
1. General information
| Official gene symbol | DOCK11 |
|---|---|
| Entrez ID | 139818 |
| Gene full name | dedicator of cytokinesis 11 |
| Other gene symbols | ACG ZIZ2 bB128O4.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9223585312 | 0.0123921432 | 0.9999902473 | 0.2196455219 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4099611686 |
| GSE13712_SHEAR | Down | -0.3466652473 |
| GSE13712_STATIC | Down | -0.1555112276 |
| GSE19018 | Up | 0.0325299916 |
| GSE19899_A1 | Down | -0.3832174054 |
| GSE19899_A2 | Down | -0.6435186960 |
| PubMed_21979375_A1 | Down | -1.7361175160 |
| PubMed_21979375_A2 | Down | -0.6219290007 |
| GSE35957 | Up | 0.0807737519 |
| GSE36640 | Down | -1.0089154826 |
| GSE54402 | Down | -0.5444332084 |
| GSE9593 | Down | -0.2642514901 |
| GSE43922 | Down | -0.7262358348 |
| GSE24585 | Down | -0.1054633284 |
| GSE37065 | Down | -0.0757386186 |
| GSE28863_A1 | Up | 0.7508927378 |
| GSE28863_A2 | Up | 0.5354259047 |
| GSE28863_A3 | Up | 0.0074229289 |
| GSE28863_A4 | Up | 0.0847441314 |
| GSE48662 | Down | -0.0758762652 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018377 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040608 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048666 | CLASH | Functional MTI (Weak) | 23622248 |
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